Skin Specimen as an Alternative to Brain Tissue for Post Mortem Rabies Diagnosis in Animals to Scale up Animal Rabies Surveillance

نویسندگان

چکیده

Background: Detection of the virus or some its specific components using WHO and OIE recommended standard laboratory tests is only way to get a reliable diagnosis rabies. Brain tissue preferred specimen for post-mortem rabies in both humans animals. Higher biosecurity requirements, skill transportation facilities required collection transport brain whole carcass one reasons poor surveillance Point care testing with simple, easy operate devices would be an ideal approach providing rapid results. Methods: The study evaluated diagnostic performance two reference tests, DFAT RTPCR on skin specimen, assess suitability as alternative post mortem sample belonging different species animals (n=90) collected at necropsy were compared Fluorescent Antibody Test RT PCR, internationally approved methods diagnosis. Results: Validation RT-PCR comparison gold gave sensitivity 98% (95% CI:94.1-100) 80% (95%CI:71.8-88.2) respectively. Specificity was 100% tests. Conclusion: findings highlight potential improving especially resource countries.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Rabies in Lowlier Animals

There is no mention in the available literature on the subject, in English or French, of naturally-occurring rabies in tortoises. Street virus, however, has been injected into brains of turtles and proved by passage into rabbit brain to have persisted for months. In the brains of Testudo mauritanica and Clemmys leprosa (a fresh-water species) it persisted for 302 and 150 days, respectively (Rem...

متن کامل

Animal bite epidemiology and surveillance for rabies postexposure prophylaxis.

OBJECTIVES To understand the epidemiology of animal bites and exposure, evaluate the animal exposure reporting system for surveillance of rabies postexposure prophylaxis (PEP), and identify opportunities to reduce PEP. DESIGN Period prevalence survey. STUDY POPULATION Pennsylvania residents in 1995. PROCEDURE Data from animal bite reports from Pennsylvania county health offices were summa...

متن کامل

14: Animal Bite Epidemiology and Surveillance for Rabies Post Exposure Prophylaxis, Iran

Background and aims: Animal bites are a significant threat to human health because of fatality of subsequent infections such as rabies. The aim of this study was to determine the epidemiology of animal bites during a five-year period in Shush County. Methods: In a descriptive cross sectional study, all cases of animal bites referred to the health centers in Shush County were investigated during...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: EAS journal of veterinary medical science

سال: 2022

ISSN: ['2663-1881', '2663-7316']

DOI: https://doi.org/10.36349/easjvms.2022.v04i04.001